Endocrine Abstracts

Background: Autoimmune polyglandular syndrome type 1 (APS-1) is a rare autosomal recessive, monogenic disease, that could be presented as a group of various symptoms, but clinical diagnosis requires existence of minimum two of three leading disorders: chronic mucocutaneous candidiasis, hypoparathyroidism, and primary adrenocortical insufficiency.Case Presentation: We report the clinical cases of two siblings with APS-1, one 28-year-old male and one 25-ye...

Background: Hyperemesis gravidarum is a rare condition with multiple causes. Diagnosis is based on clinical examination and measurement of urine ketones, serum electrolytes, and renal function. Hyperparathyroidism during pregnancy can rarely be manifested with clinical presentation of hyperemesis gravidarum with substantial maternal and fetal complications. In most cases adequate hydration, with or without forced diuresis, as well as with low calcium content diet is treatment ...

Background: Hypopituitarism is a rare clinical condition which can present as partial or complete absence of pituitary hormones. The most common cause is a sellar or parasellar mass, particularly tumour, and the golden standard for differential diagnosis is magnetic resonance imaging. Intrasellar aneurysm is an unusual cause of hypopituitarism with an estimated incidence of 0,17% of cases.Case presentation: We report a case of a 72-year-old male who was ...

Background: Past research suggests that diabetes mellitus, although with still insufficiently known mechanisms, has an effect on bone turnover.Objective of this study was to determine the level of bone metabolism parameters and vitamin D in women with postmenopausal osteoporosis and type 2 diabetes mellitus.: Material and methodsThe prospective study included 30 women with postmenopausal osteoporosis and type 2 diabetes mellitus an...

Introduction: It is known that diabetes mellitus and its complex yet insufficiently known mechanisms affect bone strength and increases the fracture risk.Objective: The aim of this study was to assess bone mass measured by lumbar spine and hip DXA, in patients suffering from diabetes mellitus according to sex and type of diabetes.Material and methods: It was a prospective study. Included 150 diabetic patients of both sexes.<p c...

Introduction: Adult-onset noninsulinoma pancreatogenous hypoglycemia syndrome (NIPHS) associated with hyperinsulinemic hypoglycemia is a very rare entity. Clinical features of NIPHS are similar to those of insulinoma. Hypoglycemia with neuroglycopenic symptoms presents the main diagnostic condition. NIPHS is often poorly responsive or unresponsive to medical management necessitating surgical intervention with resection of pancreatic tissue.Case report: W...

Introduction: The most common localization of parathyroid glands is behind the thyroid gland poles. According to different authors ectopic localization is present in 37–45.7%.Case report: Caucasian male, 31 years old, with elevated serum calcium was sent to an endocrinologist after pyelolithotothomy. He has the history of ulcerative colitis treated with anti-inflammatory therapy. Laboratory analysis: total serum calcium: 2.85 mmol/l, phosphorus: 0.6...